Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0312154
PubChem CID
Molecular Formula
C9H7N3OS
Molecular Weight
205.242 g/mol
Synonyms/Alias
[N-(1;3-thiazol-2-yl)pyridine-3-carboxamide; N-Thiazol-2-yl-nicotinamide; N-(2-Thiazolyl)nicotinamide; Oprea1_723708; Oprea1_760172; MLS001211837; CHEMBL92172; SCHEMBL3178619; HMS2842F08; STK074920; N...
InChI Key
XOXGTZLXSYSIRP-UHFFFAOYSA-N
InChI
InChI=1S/C9H7N3OS/c13-8(7-2-1-3-10-6-7)12-9-11-4-5-14-9/h1-6H,(H,11,12,13)
IUPAC Name
N-(1,3-thiazol-2-yl)pyridine-3-carboxamide
CAS Number
570406-98-3

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

21 22 0 0 0 0 0 0 0 0999 V2000
-3.3171 0.8046 0.9685 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.9574 0.5830 0.7427 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.5416 -0.225...

Experimental Data

Activity Data

Target Ion Channel
Aquaporin-4
Uniprot Accession Number
Function
Inactive
Species
Rattus norvegicus (Rat)
IC50
N/A (Not available)
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
No effect

Experimental Conditions

pH
Not mention
Holding Potential
Not specified
Temperature
18 °C
Test Method
Binding assay
Test Species
Xenopus laevis oocyte

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
14
Rotatable Bonds
2
logP
1.7904
Complexity
54.3042
TPSA (Ų)
54.88
H-Bond Donors
1
H-Bond Acceptors
4
Ring Count
2
New Search